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Description

Ironing out the details of ferroptosis

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Consistently, HIF1A also promotes GSH synthesis through transcriptional activation of GCLM and SLC7A11 , and pharmacological inhibition of SLC7A11 with erastin or sorafenib exacerbates cuproptosis 177,178

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10.1016/j.bbagen.2012.09.008 [DOI] [PMC free article] [PubMed] [Google Scholar] Mak T

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The internalization of iron by macrophages can modulate macrophage activity towards a pro-inflammatory phenotype, which may also depend on the pathway of iron intake

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Surprisingly, we still detected an induction effect of DMF on most of the factors studied despite NRF2 silencing (Fig

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Allyl isothiocyanate as a cancer chemopreventive phytochemical

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